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1. Evoluent Vertical Mouse 4
Pros:
- Keeps your wrist at near perfect handshake position
- Most intuitive DPI switching with LED indicator
- Awesome 3rd middle click button
- Comes in 3 sizes for more personalized fit
Cons:
- Quite expensive
2. Kensington Pro Fit Ergo Trackball
The Kensington Pro Fit
combines both designs
Pros:
- Vertical plus trackball design keeps wrist completely still
- 9 customizable buttons
- Physical DPI switch underneath mouse
- Supports both wireless and bluetooth
Cons:
- Higher learning curve compared to standard vertical mouse
3. Logitech MX Vertical Mouse
Pros:
- Scientifically proven to reduce muscle strain
- Premium rubber texture
- Can be simultaneously used with three devices
Cons:
- Back and forward button placed too high
4. R-Go Tools Break Vertical Ergo Mouse
Evoluent’s little brother.
Pros:
- Good alternative to the Evoluent Mouse 4
- Physical DPI switch with LED indicator
Cons:
5. J-Tech v628 Vertical Mouse

The maximum angle
of your wrist relative to the desk surface
Pros:
- Profile ideal for people with larger hands
- Detachable palm rest
Cons: